1 edition of Induced stem cells found in the catalog.
Induced stem cells
Patrick J. Sullivan
Includes bibliographical references and index.
|Statement||Patrick J. Sullivan and Elena K. Mortensen, editors|
|Series||Stem cells-laboratory and clinical research|
|LC Classifications||QH588.S83 I53 2011|
|The Physical Object|
|Pagination||x, 166 p. :|
|Number of Pages||166|
|LC Control Number||2011015374|
Pluripotent stem cells, such as embryonic stem cells (ESCs), can self-renew and differentiate into all somatic cell types. Somatic cells can be reprogrammed to become pluripotent via nuclear transfer into oocytes or through the ectopic expression of defined factors (1–4).However, exogenous pluripotency-associated factors, especially Oct4, are indispensable for establishing Cited by: Induced stem cells from healthy adults. Induced stem cells from healthy adults. If you're seeing this message, it means we're having trouble loading external resources on our website. If you're behind a web filter, please make sure that the domains * and * are unblocked.
The technique for making these so-called induced pluripotent stem (iPS) cells is less than five years old. Before then, researchers had to rely on early embryos discarded from fertility clinics to. Induced pluripotent stem cells in chronic wound healing. Induced pluripotent stem cells (iPSC) represent a groundbreaking innovation for adult-derived stem cells that carry enhanced therapeutic and translational potential. First developed in , iPSC are pluripotent stem cells derived from adult somatic by: 2.
Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if Brand: Springer New York. These reprogrammed cells are called induced pluripotent stem cells (iPS cells), and they can be made from adult cells in the skin, fatty tissue, and other sources. About the Book Author Lawrence S.B. Goldstein, PhD, one of the world's foremost experts in stem cell research, is Director of the Stem Cell Initiative at the University of California.
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Induced Pluripotent Stem (iPS) Cells: Methods and Protocols guides readers through multiple facets of stem cell biology, lineage commitment and : Hardcover. Induced Stem Cells (Stem Cells - Laboratory and Clinical Research): Medicine & Health Science Books @ Stem Cells: Therapeutic Innovations under Control traces the discovery of stem cells and induced pluripotent cells.
It establishes the link between knowledge about cell development and tissue engineering, and presents perspectives in regenerative medicine. Induced Pluripotent Stem (iPS) Cells: Methods and Protocols guides readers through multiple facets of stem cell biology, lineage commitment and differentiation.
ISBN: OCLC Number: Description: x, pages: illustrations (some color) ; 24 cm. Contents: Cryopreservation of pluripotent stem cells: from slow cooling protocols to slow cooling protocols / Hinako Ichikawa, Katsunori Sasaki --Bone tissue engineering approaches and challenges using bioactive ceramic scaffolds / Manitha B.
Nair --Induced pluripotent stem. Louis, MO, USA – Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.
Adult cells altered to have properties of embryonic stem cells (induced pluripotent stem cells). Scientists have successfully transformed regular adult cells into stem cells using genetic reprogramming. By altering the genes in the adult cells, researchers can reprogram the cells to act similarly to embryonic stem cells.
In Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols, experts in the field present a comprehensive collection of protocols designed for labs around the world. The topics covered in this detailed volume include techniques used for maintenance of hES and iPS cells in either small or large scale.
Learn about stem cell research and its potential to impact human health. Studies with mice have shown, however, that unlike embryonic stem cells induced stem cells are subject to attack by the recipient's immune system.
Treatment with stem cells in humans is experimental and can have unexpected and damaging side-effects; some methods of producing mouse stem cells with retroviruses have led to significant rates of cancer when those cells have been transferred to mice.
Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells and embryonic stem cells differ significantly.
Today many fundamental belief systems in biology are shifting towardsBrand: Springer-Verlag New York. Induced pluripotent stem cells (iPSCs) are created from more differentiated cells by transient overexpression of genes normally expressed only in pluripotent SCs.
The result of this transient overexpression is demethylation of the genome, an epigenetic reprogramming that opens up the iPSC to development programs. Recently, stem cells, including embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs), have gathered great attention in the field of Author: Said M.
Afify, Said M. Afify, Anna Sanchez Calle, Ghmkin Hassan, Ghmkin Hassan, Kazuki Kumon, Hend M. The basis of this book is formed by the theses of three talented master students: Stephanie Dooves, Dwayne Holmes and Judith Wagner. Their work discusses the recent advancements in the field of cell reprogramming.
Although it is clear that we can produce pluripotent stem cells from differentiated cells, there are still a lot of unsolved issues. Induced Stem cells. likes 1 talking about this. A goal of regenerative medicine is to restore of a damaged organ by the use of the dedifferentiated or transdifferentiated cells as therapeutic 5/5(1).
This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented.
Introduction to iPS cells. Induced pluripotent stem cells, or iPS cells, have quite similar characteristics to embryonic stem (ES) cells, such as pluripotency and unlimited self-renewal, yet can be derived from somatic cells without using embryos .Cited by: Induced pluripotent stem cell (iPSC), an emerging cell source in regenerative medicine, is also being tested for the treatment of MS.
Remarkable improvement in mobility and robust remyelination have been observed after transplantation of iPSC-derived neural cells into demyelinated by: 8.
Induced pluripotent stem cell (iPS cell), immature cell that is generated from an adult (mature) cell and that has regained the capacity to differentiate into any type of cell in the body. Induced pluripotent stem cells (iPS cells) differ from embryonic stem cells (ES cells), which form the inner cell mass of an embryo but also are pluripotent, eventually giving rise to all the cell types that.
Embryonic stem cells (ESCs) are the cells of the inner cell mass of a blastocyst, formed prior to implantation in the uterus. In human embryonic development the blastocyst stage is reached 4–5 days after fertilization, at which time it consists of 50– are pluripotent and give rise during development to all derivatives of the three germ layers: ectoderm, endoderm and :.
$ $ Ebook Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells 5/5(1).Currently, several studies have shown that the beneficial stem cell effects, especially for mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) in damaged tissue restore are not dependent on their engraftment and differentiation on the injury site, but rather to their paracrine activity.
The process of reprogramming somatic cells, the 'ordinary' cells that make up most body tissues, to become induced pluripotent stem cells (iPS cells) involves the expression of .